Is Fioricet a Controlled Substance

Edmund Murphy
Dr. Jillian Foglesong Stabile
Written by Edmund Murphy on 22 February 2022
Medically reviewed by Dr. Jillian Foglesong Stabile on 09 December 2024

The Drug Enforcement Administration (DEA) regulates substances in the U.S. under the Controlled Substances Act (CSA). This includes prescription medications such as Fioricet.

Key takeaways:
  • Fioricet is exempt from the Drug Enforcement Administration's scheduling system because it contains acetaminophen instead of aspirin, and the ratio of butalbital to acetaminophen is smaller than that of aspirin (found in Fiorinal).
  • Drugs classified as Schedule III have a lower risk for dependence and addiction but can lead to both if abused.
  • Fioricet is safe when used as prescribed, but those who abuse the drug regularly or in high doses may become dependent on the substance and can end up abusing prescriptions and acquiring the drug through illegal means when their prescription ends.

Fioricet controlled substance classification

Products that contain butalbital, caffeine, and aspirin are classified as Schedule III substances under the Controlled Substances Act (CSA). 

Fioricet, because it contains acetaminophen instead of aspirin and the ratio of butalbital to acetaminophen is smaller than that of aspirin (found in Fiorinal), is exempt from the Drug Enforcement Administration's Scheduling system. However, a few states classify Fioricet as a Schedule III controlled drug, meaning it requires a prescription and is not available over-the-counter.

Implications

Drugs classified as Schedule III have a lower risk for dependence and addiction but can lead to both if abused. The butalbital in Fioricet is a sedative barbiturate that, when used in high doses, can cause a euphoric effect.

Fioricet is safe when used as prescribed, but those who abuse the drug regularly or in high doses may become dependent on the substance and can end up abusing prescriptions and acquiring the drug through illegal means when their prescription ends. 

If you or someone you know is abusing Fioricet, then speak to an addiction specialist near you to find out what treatment is available.

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Resources:

  1. Fioricet: From Legend Drug to Schedule III-Reminders to Pharmacies and Pharmacy Personnel. Retrieved Feb 22, 2022, from

Activity History - Last updated: 09 December 2024, Published date:


Reviewer

Dr. Foglesong Stabile is a board-certified Family Physician who enjoys full-scope rural Family Medicine, including OB. As a family medicine physician, Dr. Foglesong Stabile manages a broad spectrum of health conditions.

Activity History - Medically Reviewed on 09 December 2024 and last checked on 09 December 2024

Medically reviewed by
Dr. Jillian Foglesong Stabile

Dr. Jillian Foglesong Stabile

MD, FAAFP

Reviewer

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