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Oxycodone-acetaminophen is an analgesic medication used to treat severe pain. It is available in various forms and strengths. One form is the 512 pill, produced by Mallinckrodt Pharmaceuticals. This medication should always be used exactly as prescribed, as adverse effects and risks can occur.
- The 512 oxycodone-acetaminophen pill is an analgesic pain relief, containing 5 mg of oxycodone hydrochloride and 325 mg of acetaminophen.
- This pill is only available on prescription and should be taken as directed.
- There is a risk of addiction, abuse, and side effects when using this medication.
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What is a 512 pill?
A 512 pill is a tablet containing acetaminophen and oxycodone, imprinted with 512 on one side. There are other pills, of various shapes, colors, and contents, with 512 imprinted on them, but this article refers only to the acetaminophen and oxycodone tablets. [1][2]
Mallinckrodt Pharmaceuticals produces this pill, which contains 5 mg of oxycodone hydrochloride and 325 mg of acetaminophen. Oxycodone is an opioid analgesic, and acetaminophen is a non-opioid pain relief. [3] These pills are available only with a prescription and contain oxycodone, which is a Schedule II controlled substance. This means that they can cause a risk of addiction, abuse, and misuse. This medication is prescribed to treat severe pain. [3]
How to identify a 512 pill
The 512 pill is white and round, with 512 imprinted on one side and a scored line on the other. [1]
Fake pills are produced and sold illicitly, mimicking medications such as the 512 pill. They can look almost identical to the real medication, which makes it difficult to identify. These pills often contain fentanyl or other illicitly produced substances. This can make them dangerous and potentially lethal. [4]
To ensure the use of legitimate medications, only use pills that have been prescribed by a doctor and dispensed by a pharmacist.
Side effects of 512 pills
It is common to experience side effects when starting a new medication or increasing the dosage. Typically, these side effects will be alleviated in a short time. However, if side effects persist or become problematic, consult a doctor for advice.
Common side effects of 512 pills include: [3][5]
- Drowsiness
- Dizziness
- Headache
- Stomach pain
- Constipation
- Nausea
- Vomiting
- Blurred vision
- Mood changes
- Dry mouth
- Flushing
Severe side effects
In some cases, serious side effects can occur. In the event of any of the following side effects, contact a doctor: [3][5]
- Extreme changes in heart rate
- Difficulty breathing
- Extreme drowsiness
- Chest pain
- Swelling of the face or mouth
- Swelling of the hands or feet
- Seizures
- Hallucinations
- Fever
- Confusion
- Diarrhea or vomiting that doesn’t get better
Addiction and abuse potential
512 pills contain 5 mg of oxycodone, which is an addictive substance. Oxycodone use can lead to the development of dependence and tolerance, even when it is used as prescribed. This, along with its euphoric and relaxing effects, can lead to the misuse or abuse of the medication and the development of addiction. [3][7]
Oxycodone is commonly abused in the United States and is associated with the opioid overdose epidemic. Some people abuse oxycodone pills by crushing and snorting them, or dissolving them in water and injecting the liquid. These modes of administration can increase the risk of harmful effects. [6]
Precautions
Precautions and considerations for people taking this medication include: [3][5]
- Addiction and abuse: Use with caution to help reduce the development of addiction. Do not share or misuse tablets.
- Respiratory depression: 512 pills can cause a risk of respiratory depression, particularly at the start of a new treatment.
- Dosage changes: Do not alter doses without being advised to do so by the prescribing physician.
- Withdrawal symptoms: Abruptly stopping taking the 512 pill can cause withdrawal symptoms. When treatment is discontinued, a gradual taper is recommended.
- Hypotension: This pill can cause low blood pressure. Signs of hypotension should be reported to a physician.
- Pregnancy and breastfeeding: Taking this medication while pregnant or breastfeeding could cause risks to the fetus or infant. It may be necessary to discuss treatment options with the physician before commencing treatment.
- Driving risk: This medication can cause drowsiness, so it is advised not to drive until its effects are known.
- Storage: Store this medication in a safe place, where it cannot be accessed by others or accidentally ingested by children or pets.
Contraindications & vulnerable populations
Some people may not be able to take the 512 pill or may need reduced doses, as it can cause increased risks, such as people with these conditions: [3]
- Head injury or tumors
- Gastrointestinal conditions
- Chronic lung issues
- Heart or blood pressure issues
- Seizure disorders
- History of addiction
- Adrenal issues
Drug interactions of 512 pills
Potentially serious drug interactions with 512 pills include: [3]
- Monoamine oxidase inhibitors (MAOIs): MAOIs should not be used within 14 days of taking oxycodone-acetaminophen, as it can increase the risk of serotonin syndrome or opioid toxicity.
- Serotonergic medications: Drugs that impact serotonin levels, such as antidepressants, triptans, or tramadol, can cause serotonin syndrome when taken alongside the 512 pill. Concomitant use is not recommended; if it is medically necessary, doses might need to be adjusted.
- Central nervous system (CNS) depressants: Taking this medication with other CNS depressants, such as other opioids, alcohol, or benzodiazepines, can cause dangerous CNS depression, potentially resulting in oversedation, respiratory depression, coma, or death.
Always discuss current or recent medications, substances, and supplements with the prescribing doctor before commencing a new treatment.
512 pill overdose
Taking higher doses of the 512 pill than recommended can result in overdose. It is recommended to take one tablet every 6 hours, up to a maximum daily dose of 6 tablets. Signs of an overdose of the 512 pill can include: [3][5]
- Trouble breathing
- Cold and clammy skin
- Constricted pupils
- Nausea and vomiting
- Extreme drowsiness and weakness
- Loss of consciousness
Reacting to a 512 overdose
If an overdose is suspected, call 911 immediately. Urgent or life-saving treatment may be required, as an overdose can be fatal. It can be helpful to collect necessary information before seeking medical attention, including:
- The name and information of the individual
- The number of pills ingested
- Whether the medication is prescribed
- If any other substances have been used
Treatment might include measures to ensure safe airways and breathing, administration of opioid antagonists, management of symptoms, and close monitoring. [3]
Treatment for 512 misuse and addiction
People who are misusing 512 pills of other oxycodone-acetaminophen pills might need professional support to reduce or stop their use. Prolonged and excessive misuse may have caused the development of dependence and addiction, which can require specialist treatments such as medication-assisted treatment or rehabilitation services.
The Recovered website provides information about available treatment options and local rehab centers.
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