Is Flexeril a Controlled Substance?

Edmund Murphy
Dr. Tomas Salinas
Written by Edmund Murphy on 11 January 2022
Medically reviewed by Dr. Tomas Salinas on 25 November 2024

Cyclobenzaprine, better known by the brand names Flexeril and Amrix, is not currently regulated by the DEA under the Controlled Substance Act, though this is widely contested.

Key takeaways:
  • Cyclobenzaprine, also known as Flexeril and Amrix, is still not scheduled under the Controlled Substances Act (CSA).[1]
  • In 2016 and 2017, there were over 20,000 reported cases of cyclobenzaprine abuse, with over 150 medical incidents and 5 deaths across both years.

Flexeril controlled substance status

As confirmed in a report from March 2020 by the Drug Enforcement Administration (DEA), Cyclobenzaprine, also known as Flexeril and Amrix, is still not scheduled under the Controlled Substances Act (CSA).

Implications

Cyclobenzaprine interacts with the central nervous system (CNS) as a muscle relaxant. Flexeril and Amrix are often prescribed to treat muscle pain, sprains, tenderness, and musculoskeletal pain. While the drug is safe to use on its own, the relaxing properties of the drug increase the risk of it being misused.

The DEAs research outlines growing reports of people abusing Flexeril alongside other CNS depressants, such as benzodiazepines and alcohol, in order to enhance the euphoric effects of the substances.

Research from the American Association of Poison Control Centers and the Drug Abuse Warning Network Emergency Department (DAWN ED) indicates concerning statistics surrounding Flexeril abuse:

  • In 2016 and 2017, there were over 20,000 reported cases of cyclobenzaprine abuse, with over 150 medical incidents and 5 deaths across both years.
  • There was a 101% increase in hospital room visits associated with cyclobenzaprine abuse, from around 6000 to over 12000, between 2004 and 2010.

Flexeril addiction

While Flexeril is not currently regulated under the CSA, there is strong evidence to indicate that the drug holds the potential for abuse, dependence, and addiction.

Abusing prescription medication like Flexeril can greatly increase the likelihood of developing an addiction. If you or someone you care about is at risk of becoming addicted to Flexeril, or if a drug dependence has already developed, we highly recommend contacting an addiction center for a professional assessment and further guidance or treatment for this condition.

Was this page helpful?

Your feedback allows us to continually improve our information

Resources:

  1. CYCLOBENZAPRINE (Brand Name: Flexeril®, Amrix®). Retrieved from on Jan 10, 2022.

Activity History - Last updated: 25 November 2024, Published date:


Reviewer

Tomas Salinas is a primary care physician with over three years of experience managing chronic diseases and mental health disorders. As an advocate for telehealth, Tomas has embraced digital healthcare to improve access and patient outcomes. Currently, Tomas is developing his medical writing skills, with a focus on raising awareness about the importance of chronic and mental health disease management. Tomas aims to contribute to the medical community through health communication and advocacy.

Activity History - Medically Reviewed on 25 November 2024 and last checked on 25 November 2024

Medically reviewed by
Dr. Tomas Salinas

Dr. Tomas Salinas

GP

Reviewer

Recovered Branding BG
Ready to talk about treatment? Call today. (855) 648-7288
Helpline Information

Calls to numbers marked with (I) symbols will be answered or returned by one of the treatment providers listed in our Terms and Conditions, each of which is a paid advertiser.

In calling the helpline you agree to our Terms and Conditions. We do not receive any fee or commission dependent upon which treatment or provider a caller chooses.

There is no obligation to enter treatment.

For any specific questions please email us at info@recovered.org

More on Flexeril

Flexeril Dosage

2 minutes read