Intermittent Explosive Disorder (IED)

Brittany Ferri
Dr. Jennie Stanford
Written by Brittany Ferri on 11 November 2025
Medically reviewed by Dr. Jennie Stanford on 11 November 2025

Intermittent explosive disorder (IED) causes persistent, impulsive episodes of aggression. These outbursts may be considered reactive (hostile, in-the-moment) or premeditated (also known as instrumental). Regardless of what subtype someone has, individuals with IED benefit from a combination of medications (antidepressants, mood stabilizers, or anti-anxiety medications) and psychotherapy focused on anger management. Youth with this condition can also benefit from family therapy to learn about IED, parenting techniques, and communication styles to assist with symptom management.

Key takeaways:
  • IED is a mental health condition characterized by sudden, aggressive outbursts. These may involve threatening people, destroying property, harming people, or a combination of hurtful actions.
  • IED symptoms may become worse due to substance use, but substance use does not cause this condition.
  • Medication and psychotherapy (group, family, or individual) are recommended as effective IED treatment options. Individuals with IED may use a combination of behavioral and cognitive techniques to manage their anger in a productive way.
Intermittent Explosive Disorder (IED)

What is Intermittent Explosive Disorder (IED)?

Intermittent explosive disorder, also known as IED, is a mental health condition that causes sudden and persistent episodes of aggression that are impulsive in nature. IED is set apart from other types of anger or aggression in that the behavior of someone with IED is not appropriate for the situation at hand. Individuals with IED are unable to control their impulses to express aggression, which can make this condition difficult to manage.

Subtypes of IED

Officially, there are two major subtypes of IED-related aggression: instrumental and hostile.

Instrumental aggression

Instrumental aggression, also known as premeditated aggression, has three main criteria for diagnosis:

  • Aggressive behavior that does not primarily stem from anger
  • Aggressive behavior that is closely related to a certain goal or reinforcer, such as seeking justice or receiving a reward
  • Aggressive behavior that involves prior planning (even brief forethought).  

Behaviors related to instrumental aggression do not need to be thoroughly planned, as even brief forethought constitutes planning.

Hostile aggression

Hostile aggression does not involve the same level of premeditation as the other subtype, which is why it is also called reactive aggression. The three criteria for the hostile aggression IED subtype involve:

  1. Acting aggressively as a result of anger
  2. Displaying behaviors that aim to injure a target
  3. Engaging in aggression that was planned very little or not at all.

Informal subtypes

Some sources also identify informal subtypes of this condition based on who or what is impacted by IED episodes. These subtypes include attacks that fit one of these criteria:

  • Hurt people only
  • Involve property destruction and hurting people
  • Involve property destruction only
  • Involve property destruction and threatening people
  • Threaten people only

Symptoms and behavioral signs of IED

The core features of this condition include anger, aggression, and impulsivity. These can take the form of several emotional and behavioral symptoms, which include:

  • Physical aggression aimed at property, other individuals, or both
  • Verbal abuse, which may include threatening others
  • Acting in an angry, impulsive manner with intense and frequent outbursts
  • Engaging in self-harm behaviors

During outbursts, individuals experience emotional symptoms (with a highly irritable mood and strong feelings of rage) and physical symptoms (tremors, muscle tension, chest tightness, sweating, tachycardia, and headaches). After outbursts, individuals experience feelings of shame, embarrassment, and guilt.

Causes and risk factors

Research suggests that IED is at least partly a genetic condition. Individuals who have first-degree relatives (e.g., parents or siblings) with this condition are at a significantly higher risk of developing IED than individuals without this history. Neglect, trauma, abuse, and other types of adverse childhood events also raise someone’s risk of developing IED.

There has been some research looking into the connection between substance use disorder (SUD) and IED. While substance use does increase someone’s risk of displaying aggressive behavior, it does not necessarily raise someone’s risk of developing IED. However, evidence does show that individuals with IED are more likely to develop substance use disorders than the general population. In fact, one study showed that daily and weekly substance consumption increased alongside the severity of someone’s IED-related aggression. While there is a strong link between these two conditions, one does not definitively cause the other.

Diagnosis

Mental health professionals must complete a psychiatric evaluation before diagnosing someone with IED. This includes taking someone’s medical history and discussing the person’s functioning and behavior. It is important for providers to be thorough while taking a patient’s history, as someone cannot receive a diagnosis of IED if they have aggressive and impulsive outbursts attributed to another condition.

Mental health professionals utilize the IED criteria in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) to determine whether or not the patient’s clinical presentation matches. This is the most definitive way to diagnose IED.

Effects of IED on relationships and daily life

If left untreated, IED can lead to many adverse effects that impact someone’s life:

  • Isolation from family and friends
  • Difficulty fulfilling work duties
  • Legal concerns
  • Job loss (potentially leading to financial instability)
  • Strained relationships with significant others, including increased conflict and domestic violence
  • Academic difficulties, including poor performance and attendance concerns
  • Substance misuse, potentially leading to substance use disorder(s)

Complications & comorbidities

Individuals with IED are at a heightened risk of co-occurring psychiatric and medical conditions. If IED is not treated, it can make it more difficult to properly manage other conditions, such as depression, anxiety, hypertension, and cardiovascular conditions. While people with IED typically display aggression in an outward manner, they may engage in self-harm behaviors in an attempt to control their impulses.

IED and substance use disorder comorbidity

Research shows there is a relationship between IED and substance use disorder. One important study debunked the idea that anxiety, depression, and other mental health concerns are the cause of IED-related aggression. In addition, evidence shows that someone with IED is not always destined to develop substance use concerns. However, in individuals who have both SUD and IED, aggressive episodes do tend to develop before chronic substance use concerns do.  

This pattern can help mental health providers and families engage in preventive care measures (such as screening efforts and community resources) to assist with managing IED-related concerns before they negatively affect a person’s life.

Treatment options

Individuals with IED are most often advised to participate in psychotherapy to help manage their condition. Cognitive-behavioral therapy (CBT) can help individuals learn to manage their impulses and develop healthier behaviors. CBT concepts (such as cognitive restructuring) can help those with IED shift their outlook on difficult situations that may lead to anger. CBT also teaches problem-solving and coping skills to help manage anger when emotional tension begins to build.

Group therapy may be particularly useful for adolescents and young adults who have difficulty with social skills as a result of their condition. Family therapy is beneficial for children and adolescents with IED. This form of therapy can help parents, caregivers, and siblings learn about the condition itself as well as communication styles and parenting techniques to help with the therapeutic process.

Evidence shows that pairing this treatment with medication is also quite effective. In terms of medications, individuals may be prescribed selective serotonin reuptake inhibitors (SSRIs). Other options include mood stabilizers, which can help individuals with severe aggression experience a more balanced mood. Some individuals may also benefit from anti-anxiety medications to assist with irritable moods that may trigger aggression.

Coping and anger management techniques: How to calm down with IED

A major focus of treatment for IED is anger management training to help individuals control their impulses in a healthy manner. As mentioned earlier, CBT is helpful for individuals with IED. This modality uses cognitive and behavioral techniques together to create healthier skills for living. This is applicable to anger, along with many other mental health concerns. These are some behavioral approaches to assist with anger management:

  • Stepping away: Sometimes it helps to remove yourself from a situation temporarily and allow yourself time and space to calm down. This is a proactive way to counter impulses before they arise, so it’s best done in advance before tension builds too much.
  • Relaxation techniques: There are a host of options in this category that can be used to center the body and mind together. Some examples include progressive muscle relaxation, deep breathing, guided imagery, and meditation.
  • Physical activity: All forms of exercise assist in releasing endorphins to help boost mood. However, your mental health professional may recommend that individuals with IED stay away from exercises, such as boxing and karate, as these may make it more difficult to fight aggressive impulses.

Conversely, these are some cognitive approaches geared toward anger management:

  • Adjust negative thoughts: If you have negative beliefs about the world or other people, they may fuel irritability and anger. You can prevent mental tension from building by shifting these thoughts to those that are more positive or realistic.
  • Look at situations differently: Try to adopt a different perspective when you are in certain situations. For example, instead of making assumptions that someone’s actions were the result of bad intentions, try to understand that things don’t always work out the way you want.
  • Identify triggers: By recognizing what around you tends to cause irritability and difficult feelings, you can learn to avoid certain situations or prepare yourself with strategies to manage those feelings.

How to support someone with IED

One of the best ways to support someone with IED is to learn about the condition. This not only helps bring awareness to intermittent explosive disorder, but also helps a person’s loved ones gain a better understanding of them.

In addition, loved ones of those with IED should exercise patience and support them in their therapy journey. This may include participating in family therapy with them or simply encouraging them to talk about what they are learning.

Recovery & long-term outlook with treatment

With comprehensive treatment, people with intermittent explosive disorder can learn to manage their impulses in a way that allows them to do well in academic, occupational, and social settings. It is important to actively participate in and adhere to IED treatment in order to have a good prognosis. Individuals with IED also benefit from social support (such as reliable friends and family) to assist them in learning to live with their condition.

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Resources:

  1. Fanning, J. R., Coleman, M., Lee, R., & Coccaro, E. F. (2019). Subtypes of aggression in intermittent explosive disorder. Journal of Psychiatric Research, 109, 164–172.
  2. Scott, K. M., de Vries, Y. A., Aguilar-Gaxiola, S., Al-Hamzawi, A., Alonso, J., Bromet, E. J., Bunting, B., Caldas-de-Almeida, J. M., Cía, A., Florescu, S., Gureje, O., Hu, C. Y., Karam, E. G., Karam, A., Kawakami, N., Kessler, R. C., Lee, S., McGrath, J., Oladeji, B., Posada-Villa, J., … World Mental Health Surveys collaborators (2020). Intermittent explosive disorder subtypes in the general population: association with comorbidity, impairment and suicidality. Epidemiology and Psychiatric Sciences, 29, e138.
  3. Coccaro, E. F., Fridberg, D. J., Fanning, J. R., Grant, J. E., King, A. C., & Lee, R. (2016). Substance use disorders: Relationship with intermittent explosive disorder and with aggression, anger, and impulsivity. Journal of Psychiatric Research, 81, 127–132.
  4. Paliakkara, J., Ellenberg, S., Ursino, A., Smith, A. A., Evans, J., Strayhorn, J., Faraone, S. V., & Zhang-James, Y. (2024). A systematic review of the etiology and neurobiology of Intermittent Explosive Disorder. MedRxiv: The preprint server for health sciences, 2024.09.12.24313573.
  5. Coccaro, E. F., Fridberg, D. J., Fanning, J. R., Grant, J. E., King, A. C., & Lee, R. (2016). Substance use disorders: Relationship with intermittent explosive disorder and with aggression, anger, and impulsivity. Journal of Psychiatric Research, 81, 127–132.
  6. Coccaro, E.F., Fanning, J.R., & Lee, R. (2017). Intermittent Explosive Disorder and Substance Use Disorder: Analysis of the National Comorbidity Survey Replication Sample. J Clin Psychiatry, 78(6), 697-702.
  7. Wood, M. (2017). Aggression disorder linked to greater risk of substance abuse. Retrieved from

Activity History - Last updated: 11 November 2025, Published date:


Reviewer

Dr. Jennie Stanford

MD, FAAFP, DipABOM

Jennie Stanford, MD, FAAFP, DipABOM is a dual board-certified physician in both family medicine and obesity medicine. She has a wide range of clinical experiences, ranging from years of traditional clinic practice to hospitalist care to performing peer quality review to ensure optimal patient care.

Activity History - Medically Reviewed on 10 November 2025 and last checked on 11 November 2025

Medically reviewed by
Dr. Jennie Stanford

Dr. Jennie Stanford

MD, FAAFP, DipABOM

Reviewer

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